Handbook of Stem Cell Therapy

The handbook comprehensively reviews the therapeutic potential of stem cells and stem cell-based cell-free strategies for the treatment of diseases. The initial chapters discuss the diverse applications of the stem and progenitor cells, including skeletal myoblasts, endothelial progenitor cells, adipose tissue-derived stem cells, induced pluripotent stem cells, mesenchymal stem cells, and neuronal stem cells in myocardial repair, inflammatory bowel disease, cognitive deficits, wound healing, retinal disorders, and COVID-19. The subsequent chapter summarizes methods for identifying and characterizing mesenchymal stem cells and discusses their properties and surface markers used for their prospective isolation. It also covers the therapeutic potential of mesenchymal stem cells in regenerative medicine. In turn, the book reviews the impact of stem cells derived secretome on various biological processes such as angiogenesis, neurogenesis, tissue repair, immunomodulation, musculoskeletal pathologies, wound healing, anti-fibrotic, and anti-tumor for tissue maintenance and regeneration.
Lastly, it summarizes treatment advantages, opportunities, and shortcomings in stem cell-based therapy, potentially helping to refine future trials and translate them from experimental to clinical studies. This reference book is a valuable resource for researchers involved in stem cell research to understand the multifaceted therapeutic applications of stem cells.